Canis ISSN: 2398-2942

Skin: erythema multiforme

Contributor(s): Prof Douglass Macintire, Richard Squires, Charlie Walker

Introduction

  • Uncommon, acute, self-limiting eruption of skin and/or mucous membranes.
  • Cause: drugs, infections, idiopathic.
  • Signs: maculopapular rash, vesiculation, depression, anorexia.
  • Diagnosis: history, clinical signs, histopathology.
  • Treatment: supportive care +/- immunosuppressive chemotherapy.
  • Prognosis: good.

Pathogenesis

Etiology

Pathophysiology

  • Necrotizing condition of the epidermis with an interface reaction.
  • Circulating immune complexes are found in man.

Timecourse

  • Acute self-limiting disease.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lewis D T (1998) Life-threatening dermatoses in dogs. Comp Cont Ed Prac Vet 20 (3), 271-283 VetMedResource.
  • Delmage D A and Payne-Johnson C E (1991) Erythema multiforme in a Dobermann on trimethoprim sulphamethoxazole therapy. JSAP 32 (12), 635-639 VetMedResource.
  • Medleau L, Shanley K J, Rakich P M and Goldschmidt M H (1990) Trimethoprim-sulfonamide-associated drug eruptions in dogs. JAAHA 26 (3), 305-311 VetMedResource.


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