ISSN 2398-2969      

Skin: candidiasis

icanis

Synonym(s): Moniliasis, Thrush


Introduction

  • Rare, opportunistic infection. Requires predisposing factors to cause disease.
  • Cause:Candida albicans usually involved.
  • Signs: predilection sites are external ear, mucocutaneous areas, intertriginous areas and nail bed.
  • Presents as whitish plaques covering non-healing ulcer on oral mucosa, or red plaques on skin.
  • Diagnosis: cytopathology, mycology, biopsy.
  • Treatment: correction of predisposing factors, antifungal drugs.
  • Prognosis: responds to antifungal agents provided predisposing factors corrected.

Pathogenesis

Predisposing factors

General

  • Tissue damage: burns, maceration, catheter implantation.
  • Prolonged antibiotic therapy.
  • Immunosuppression, eg diabetes mellitus Diabetes mellitus , hyperadrenocorticism Hyperadrenocorticism , or corticosteroid therapy.

Pathophysiology

  • Normal inhabitant of intestinal, upper respiratory and genital tracts.
  • Opportunistic infection requiring breakdown of normal surface defences, eg excessive moisture, tissue maceration, indwelling catheter.
  • Invasion of keratin → ulcerative lesions.
  • Breakdown of normal surface defences or disruption of microflora allows Candida spp Candida albicans to invade surface tissues and produce ulceration.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

Other sources of information

  • Greene C E & Chandler F W (1990) Candidiasis. In: Infectious diseases of dogs and cats. Greene C E (ed) Philadelphia: Saunders. p 723.

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