Canis ISSN: 2398-2942

Skin: calcinosis circumscripta

Synonym(s): Apocrine cystic calcinosis, multiloculated subcutaneous granuloma, tumoral calcinosis, lipocalcinosis

Contributor(s): Kyle Braund

Introduction

  • Errant deposits of calcium salts in subcutaneous tissue, around vertebrae, tongue or attached to tendons/joint capsules.
  • Cause: unknown.
  • Incidence: large breeds (especially Great Dane, German Shepherd Dog), young animals.
  • Sites: mouth, foot pads, cervical region.
  • Signs: non-painful, well-circumscribed, hard swellings.
  • Treatment: surgical excision.
  • Prognosis: good.

Pathogenesis

Etiology

  • Unknown but may be associated with sites of previous wounds or SC injections.
  • Exogenous administration of calcium or vitamin D.

Specific

  • Some animals may have renal disease. The prevalence of the condition in young large-breed dogs, particularly German Shepherds, Great Danes and Viszlas, suggests possible hereditary predeliction.

Pathophysiology

  • Errant deposition of calcium salts in soft tissue and peri-articular areas.
  • Similar lesions seen in uremia Uremia , chronic renal failure Kidney: chronic kidney disease (CKD) and primary hyperparathyroidism.
  • Remains obscure.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Van Ham L M et al (1995) Use of computed tomography and computed tomographic myelography for assessment of spinal tumoral calcinosis in a dog. Vet Radiol Ultrasound 36 (2), 115-118 VetMedResource.
  • Lewis D G & Kelly D F (1990) Calcinosis circumscripta in dogs as a cause of spinal ataxia. JSAP 31 (1), 35-37 VetMedResource.
  • Scott D W & Buerger R G (1988) Idiopathic calcinosis circumscripta in the dog - a retrospective analysis of 130 cases. JAAHA 24 (6), 651-658 VetMedResource.

Other sources of information

  • Braund K G (2002)Degerative Structural and Compressive Disorders. In:Clinical Neurology in Small Animals - Localization, Diagnosis and Treatment.Ed K G Braund. Ithaca: International Veterinary Information Service (www.ivis.org). Document no B0218.0202.


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