Canis ISSN: 2398-2942

Skin: benign familial chronic pemphigus

Contributor(s): David Scarff, Susan E Shaw

Introduction

  • Extremely rare disorder.
  • Signs: easily damaged skin, alopecia, erythema.
  • Recognised in English Setter and English Setter crosses.
  • Diagnosis: histopathology.
  • Treatment: none.
  • Prognosis: incurable but lesions often asymptomatic.

Pathogenesis

Etiology

  • Familial.

Pathophysiology

  • Presumed disorder of cell cohesion.

Timecourse

  • Persists throughout life.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Sueki H, Shanley K, Goldschmidt M H, Lazarus G S & Murphy G F (1997) Dominantly inherited epidermal acantholysis in dogs, simulating human benign familial chronic pemphigus (Hailey-Hailey disease). Br J Dermatol 136 (2), 190-196 PubMed.

Other sources of information

  • Scott D W, Miller W H & Griffin C E (1995)Small Animal Dermatology.5th edn. Philadelphia: W B Saunders. ISBN 0 7216 4850 9.
  • Yager J A & Wilcock B P (1994)Color Atlas and Text of Surgical Pathology of the Dog and Cat.London: Wolfe Publishing. Mosby Year Book Europe. ISBN 0 7234 1827 6.
  • Gross T L, Irkhe P J & Walder E J (1992)Veterinary Dermatopathology.St Louis: Mosby Year Book. ISBN 0 8016 5809 8.


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