Canis ISSN: 2398-2942

Salivary gland: necrotizing sialometaplasia

Synonym(s): Sialadenitis, Salivary gland infarction, Salivary gland necrosis

Contributor(s): Rosa Ragni

Introduction

  • Rare inflammatory process confined to mandibular glands.
  • Cause: unknown: viral, immune-mediated.
  • Signs: acute pain and swelling of glands.
  • Treatment: poor response to treatment- medical/surgical.
  • Prognosis: guarded.

Pathogenesis

Etiology

  • Unknown: ?viral, ?immune-mediated, ?compartment syndrome.

Specific

  • Spirocercosis Canine spirocercosis /other esophageal disease sometimes associated with salivary signs.

Pathophysiology

  • Proposed possible pathogeneses:
    • Similar to hypertrophic osteopathy Hypertrophic osteopathy , but with salivary glands instead of limbs as efferent target since lesions may regress on treatment of associated pathology (esophageal disease).
    • Compartment syndrome: necrosis resulting from rapidly developing swelling confined in a structure with a tight and strong capsule.

Timecourse

  • Weeks to months.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Kim H Y, Woo G H et al (2010) Necrotizing sialometaplasia of the parotid gland in a dog. J Vet Diagn Invest 22 (6), 975-977 PubMed.
  • Schroeder H & Berry W L (1998) Salivary gland necrosis in dogs - a retrospective study of 19 cases. JSAP 39 (3), 121-125 PubMed.
  • Brooks D G, Hottinger H A, Dunstan R W (1995) Canine necrotizing sialometaplasia: a case report and reveiw of the literature. JAAHA 31 (1), 21-25 PubMed.
  • Cooke M M & Guilford W G (1992) Salivary gland necrosis in a wire-haired fox terrier. NZ Vet J 40 (2), 69-72 PubMed.
  • Spangler W L & Culbertson M R (1991) Salivary gland disease in dogs and cats 245 cases (1985-1988). JAVMA 198 (3), 465-469 PubMed.

Other sources of information

  • Dunning D (2003)Oral cavity: tongue, lips, cheeks, pharynx, and salivary glands.In:Textbook of Small Animal Surgery.3rd edn. Slatter D (ed), W B Saunders, Philadelphia, pp 553-561.
  • Hedlund C S (2002)Surgery of the oral cavity and oropharynx.In:Small Animal Surgery. 2nd edn, T W Fossum (ed), Mosby, St. Louis, pp 274-307.
  • Knecht C D (1998)Salivary glands.In:Current techniques in Small Animal Surgery.4th edn, Bojrab M J (ed), Williams and Wilkins, Baltimore, pp183-186.


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