Canis ISSN: 2398-2942

Pheochromocytoma

Synonym(s): Pheochromocytoma

Contributor(s): David Bruyette

Introduction

  • Cause: tumors derived from chromaffin cells in adrenal medulla; occasionally extra-adrenal.
  • May be malignant; if so, may invade caudal vena cava or metastasize to lung, liver or bone.
  • Signs: can be incidental finding at PM or vague systemic signs, ie intermittent tachycardia, hypertension, excitability, ataxia and collapse.
  • Diagnosis: radiography, biochemistry, hematology.
  • Treatment: surgery.
  • Prognosis: good if surgery successful, no metastases, concurrent illness treated also.

Pathogenesis

Pathophysiology

  • Signs related to secretion of catecholamines and their systemic effects.

Timecourse

  • Weeks to years.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Louvet A, Lazard P & Denis B (2005) Phaeochromocytoma treated by en bloc resection including the suprarenal caudal vena cava in a dogJSAP 46 (12), 591-596 PubMed.
  • Schoeman J P & Stidworthy M F (2001) Budd-Chiari-like syndrome associated with an adrenal phaeochromocytoma in a dog. JSAP 42 (4), 191-194 PubMed.
  • Rosenstein D S (2000) Diagnostic imaging in canine pheochromocytoma. Vet Rad Ultra 41 (6), 499-506 PubMed.
  • Platt S R et al (1998) Pheochromocytoma in the vertebral canal of two dogs. JAAHA 34 (5), 365-371 PubMed.
  • Thuróczy J et al (1998) Multiple endocrine neoplasms in a dog - corticotrophic tumor, bilateral adrenocortical tumors, and pheochromocytoma. Vet Quart 20 (2), 56-61 VetMedResource.
  • Barthez P Y et al (1997) Pheochromocytoma in dogs - 61 cases (1984-1995). JVIM 11 (5), 272-278 PubMed.
  • Bouayad H et al (1987) Pheochromocytoma in dogs - 13 cases (1980-1985). JAVMA 191 (12), 1610-5 PubMed.
  • Twedt D C & Wheeler S L (1984) Pheochromocytoma in the dog. Vet Clin N Am 14 (4), 767-82 PubMed.


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