Canis ISSN: 2398-2942

Pericardium: hemangiosarcoma

Contributor(s): Serena Brownlie, Mark Rishniw

Introduction

  • May affect right atrium, right atrioventricular junction or right ventricle alone or other sites (spleen, etc).
  • Vascular tumor - often ruptures and bleeds into pericardial space.
  • Sudden build-up of pericardial blood leads to increased pericardial pressure, which compromises atrial and ventricular filling.
  • Signs: collapse, output failure. Ventricular or supraventricular dysrhythmias.

Pathogenesis

Etiology

  • Not known.

Predisposing factors

General
  • Breed.

Pathophysiology

  • Hemangiosarcoma → frequently affects right atrium → pericardial sac → other areas of the heart → pericardial fluid.

Timecourse

  • Apparent acute onset → recurrence of signs common → usually fatal within weeks/months.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Weisse C, Soares N, Beal M W, Steffey M A, Drobatz K J & Henry C J (2005) Survival times in dogs with right atrial hemangiosarcoma treated by menas of surgical resection with or without adjuvant chemotherapy: 23 cases (1986-2000). JAVMA 226 (4), 575-579 PubMed.
  • Shaw S P, Rozanski E A & Rush J E (2004) Cardiac troponins I and T in dogs with pericardial effusion. J Vet Intern Med 18 (3), 322-324 PubMed.
  • Fine D M, Tobias A H & Jacob K A (2003) Use of pericardial fluid pH to distinguish between idiopathic and neoplastic effusions. J Vet Intern Med 17 (4), 525-529 PubMed.
  • Bussadori C, Grasso A & Santilli R A (1998) Percutaneous pericardiotomy with balloon catheter in the treatment of malignant pericardial effusion in dogs. Radiol Med 96 (5), 503-506 PubMed.
  • Cobb M A, Boswood A, Griffin G M & McEvoy E J (1996) Percutaneous balloon pericardiotomy for the management of malignant pericardial effusion in two dogs. JSAP 37 (11), 549-551 PubMed.
  • Cobb M A & Brownlie S E (1992) Intrapericardial neoplasia in 14 dogs. JSAP 33 (7), 309-316 PubMed.
  • Aronsohn A (1985) Cardiac hemangiosarcoma in the dog - a review of 38 cases. JAVMA 187 (9), 922-926 PubMed.


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