Canis ISSN: 2398-2942 Kidney: agenesis Introduction Introduction Absence of one or both kidneys. Cause: failure of mesonephric duct which in turn fails to stimulate nephron differentiation from metanephros. Signs: normal kidney often hypertrophied . Possible increased risk of neoplastic development in normal kidney. Often other genital anomalies. Treatment: none possible. Diagnosis: radiography, laboratory tests, histopathology. Prognosis: poor. Further ReadingPublicationsRefereed papers Recent references from PubMed and VetMedResource.