Canis ISSN: 2398-2942

Infectious infertility in the female

Contributor(s): Nick Carmichael, Autumn P Davidson

Introduction

Pathogenesis

Etiology

  • Brucella canis; not in UK although is a serious problem in USA, South America, some European countries.
  • Canine herpesvirus (CHV) Canine herpesvirus.
  • (Canine parvovirus Canine parvovirus.)
  • Toxoplasma gondii Toxoplasma gondii.
  • Other bacteria andMycoplasmaspp, if intra-uterine.

Predisposing factors

General
  • Contact, venereal and general, with other dogs (Brucella canis, CHV).
  • OtherBrucellaspp: ingestion of infected milk, meat, aborted fetuses and placentae.

Pathophysiology

  • Venereal/contact with infected dog or infected material → localization of organism in genital tract → endometritis → failure to conceive and/or placentitis → early termination of pregnancy.
  • 'Non-specific' causes - probably sporadic ascending or systemic opportunistic infections.

Epidemiology

  • Herpes infection only problematic if acquired in the innocent bitch last 3 weeks of pregnancy - unable to pass antibodies to puppies.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Barton C (1997) Canine brucellosis. Reproductive problems. Vet Clin North Am 7, 705-710.
  • Okuda Y, Hashimoto A, Yamaguchi T, Fukushi H, Mori S, Tani M, Hirai K & Carmichael L (1993) Repeated canine herpesvirus (CHV) reactivation in dogs by an immunosuppressive drug. Cornell Vet 83 (4), 291-302 PubMed.

Other sources of information

  • Feldman E C & Nelson R W (1996)Brucellosis and transmissible venereal tumor.In:Canine and Feline Endocrinology and Reproduction.London: W B Saunders. pp 664-671.


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