Canis ISSN: 2398-2942

Hemangiosarcoma

Synonym(s): Angiosarcoma, hemangioendothelioma, HSA

Contributor(s): Malcolm Brearley, Jane Dobson, Laura Garrett

Introduction

  • Malignant tumor arising from blood vessel endothelium.

Pathogenesis

Pathophysiology

  • Enlarging mass.
  • Vascular channels within mass lead to stagnation of blood and predispose to disseminated intravascular coagulation, as well as causing microangiopathic disease.
  • Rupture of vascular mass leads to excessive hemorrhage.

Timecourse

  • Depends on site.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Chun R (1999) Feline and canine hemangiosarcoma. Comp Cont Ed 21 (7), 622-652 VetMedResource.
  • Edwards N J (1996) The diagnostic value of pericardial fluid pH determination. JAAHA 32 (1), 63-67 PubMed.
  • Ogilvie G K et al (1996) Surgery and doxorubicin in dogs with hemangiosarcoma. J Vet Intern Med 10 (6), 379-384 PubMed.
  • Ward H et al (1994) Cutaneous hemangiosarcoma in 25 dogs - a retrospective study. J Vet Intern Med 8 (5), 345-348 PubMed.
  • Sorenmo K U, Jeglum K A & Helfand S C (1993) Chemotherapy of canine hemangiosarcoma with doxorubicin and cyclophosphamide. J Vet Intern Med 7 (6), 370-376 PubMed.
  • Hammer A S et al (1991) Hemostatic abnormalities in dogs with hemangiosarcoma. J Vet Intern Med 5 (1), 11-14 PubMed.
  • Hargis A M & Fledman B F (1991) Evaluation of hemostatic defects secondary to vascular tumors in dogs - 11 cases (1983-1988). JAVMA 198 (5), 891-894 PubMed.
  • Aronsohn M (1985) Cardiac hemangiosarcoma in the dog - a review of 38 cases. JAVMA 187 (9), 922-926 PubMed.


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