Canis ISSN: 2398-2942

Eyelid: neoplasia

Contributor(s): David L Williams, James Oliver

Introduction

  • Cause: most commonly epithelial in origin and benign.
  • Signs: eyelid mass, ectropion/entropion, trichiasis, keratitis, ocular discharge.
  • Diagnosis: histopathological examination of biopsy specimen.
  • Treatment: surgical excision.
  • Prognosis: usually good.

Pathogenesis

Etiology

Pathophysiology

  • Meibomian gland adenomas and adenocarcinomas:
    • Erupt through eyelid margin or palbebral conjunctiva.
    • May ulcerate and hemorrhage.
    • Can cause local irritation.
  • Melanomas - two types recognized:
    • Those arising from skin tend to be minimally invasive and are excised with low recurrence rates.
    • Those arising from eyelid margin act more aggressive locally Eyelid melanoma.
  • Fibromas and fibrosarcomas Fibrosarcoma can be locally invasive.
  • Papillomas:
    • May be viral in origin and may regress spontaneously Eyelid squamous papilloma Eyelid viral papilloma Eyelid papilloma.

Timecourse

  • Usually slowly growing over months/years.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Romkes G, Klopfleisch R, Eule J C (2014) Evaluation of one-vs two-layered closure after wedge exicsion of 43 eyelid tumors in dogs. Vet Ophthalmol 17 (1), 32-40 PubMed.
  • Wiggans K T, Hoover C E, Ehrhart E J et al (2013) Malignant transformation of a putative eyelid papilloma to squamous cell carcinoma in a dog. Vet Ophthalmol 16 Suppl 1, 105-112 PubMed.
  • Van Der Woerdt A (2004) Adnexal surgery in dogs and cats. Vet Ophthamol 7, 284-290 PubMed.

Other sources of information

  • Gould D & McLellan G (2014)BSAVA Manual of Small Animal Ophthalmology.3rd edn.
  • Gelatt K N (2013)Veterinary Ophthalmology.5th edn. Lippincott, Williams & Wilkins.


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