Canis ISSN: 2398-2942

Diarrhea: due to systemic illness

Introduction

  • Cause: usually major organ dysfunction.
  • Signs: diarrhea in association with signs of underlying disease.
  • Diagnosis: identify underlying hepatic disease.
  • Treatment: manage underlying condition and symptomatic treatment of disease.
  • Prognosis: depends on ability to treat underlying disease.

Pathogenesis

Pathophysiology



Congestive heart failure
  • Elevated central venous pressure → abnormal drainage from intestine, blood and lymph → oedema → may cause increased intestinal permability and diarrhea.
Hepatic failure
  • Portal hypertension → stasis in intestinal draining veins → impaired absorption and mucosal edema → lymphangiectasia.
  • Impaired hepatic function/obstruction of bile duct → reduced delivery of bile acids to duodenum → impaired fat digestion/absorption → diarrhea.

Diagnosis

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Outcomes

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Further Reading

Publications

Refereed papers


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