Canis ISSN: 2398-2942

Chronic interstitial nephritis

Contributor(s): Phil Nicholls, Melissa Wallace

Introduction

  • A common cause of chronic renal failure.
  • Cause: usually unknown.
  • Diagnosis: histopathology, exclusion of specific diseases such as pyelonephritis, glomerulonephritis, renal amyloidosis and urolithiasis.
  • See chronic renal failure Kidney: chronic kidney disease (CKD).

Pathogenesis

Etiology

  • Often unknown etiology.
  • Leptospirosis Leptospira icterohemorrhagiae or canine adenovirus-1 Canine adenovirus type 1 may play a possible role but are probably rare.
  • Any prior renal insult or disease of sufficient magnitude can result in gradually progressive renal disease (chronic interstitial nephritis).

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Macdougall D F et al (1986) Canine chronic renal disease - prevalence and types of glomerulonephritis in the dog. Kidney Int 29 (6), 1144-1151 PubMed.
  • Wright N G et al (1983) Experimental canine adenovirus glomerulonephritis - histological, immunofluorescence and ultrastructural features of the early glomerular changes. Br J Exp Pathol 64 (3), 312-319 PubMed.


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