Canis ISSN: 2398-2942

Brachial plexus: neuropathy

Synonym(s): Brachial plexus neuropathyBrachial plexus neuritis

Contributor(s): Kyle Braund

Introduction

  • Extremely rare condition.
  • Cause: possibly allergic or hypersensitivity reaction to prophylactic inoculation or food.
  • Signs: acute onset thoracic limb paresis, with hyporeflexia, hypotonia, and possibly facial nerve deficits; muscle atrophy develops after 7-10 days.

Pathogenesis

Etiology

  • Immune-mediated reaction, eg triggered by prophylactic inoculation or diet.
  • The proposed pathogenesis is that the allergic condition produces spinal nerve swelling, and subsequent compression, at the level of the intervertebral foramina.

Specific

  • All horse meat or all beef diet.
  • Vaccination (modified live rabies virus).

Pathophysiology

  • Exposure to allergen → spinal nerve swelling → spinal nerve compression → nerve degeneration and demyelination → loss of function of nerve → decrease in muscle tone → absent or reduced spinal reflexes → neurogenic muscle atrophy.

Timecourse

  • 1-3 days.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Steinberg H S (1988) Brachial plexus injuries and dysfunctions. Vet Clin North Am 18 (3), 565-580 PubMed.
  • Alexander J W et al (1974) A case of brachial plexus neuropathy in a dog. JAAHA 10 (5), 515-516 VetMedResource.
  • Cummings J F et al (1973) Canine brachial plexus neuritis - a syndrome resembling serum neuritis in man. Cornell Vet 63 (4), 589-617 PubMed.


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