Canis ISSN: 2398-2942

Acute metritis

Synonym(s): Post-partum metritis

Contributor(s): Mushtaq Memon

Introduction

  • Cause: usually develops within 1 week of whelping (also abortion, mating, artificial insemination (AI) or normal estrus).
  • Signs: vaginal discharge: sanguinous to purulent.
  • Diagnosis: signs, imaging.
  • Treatment: broad-spectrum antibiotics, supportive, follow-up hysterectomy.
  • Prognosis: guarded depending on condition of bitch, potentially fatal if uterus ruptures.

Pathogenesis

Etiology

  • Usually ascending bacterial infection: gram-negative, egE. coli,Staphylococcusspp,Streptococcusspp andCorynebacteriumspp.

Predisposing factors

General

Specific

Pathophysiology

  • Bacteria normally found in → uterus → proliferate in lochia → endotoxin release → :
    • Interference with ADH (see pyometra complex Pyometra ) → dehydration, uremia.
    • Pathogen chemotaxis → neutrophilia → pooling of neutrophils in uterus → left shift leukogram.

Timecourse

  • Usually within 1 week of whelping (or other predisposing event).

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Watts J R & Wright P J (1995) Investigating uterine disease in the bitch: uterine cannulation for cytology, microbiology and hysteroscopy. JSAP 36 (5), 201-206 PubMed.

Other sources of information

  • Magne M L (1986)Acute metritis in the bitch.In:Current Therapy in Theriogenology.2nd edn. Morrow D A (ed). London: W B Saunders (a good review).


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