Canis ISSN: 2398-2942

Acanthosis nigricans

Contributor(s): Flemming Kristensen, David Scarff

Introduction

  • Uncommon cutaneous reaction pattern.
  • Cause: inherited or due to hypersensitivity, trauma or endocrinopathy.
  • Signs: melanosis, acanthosis and lichenification in flexures, especially axilla Acanthosis nigricans.
  • Idiopathic in Dachshund.
  • Secondary feature with several skin disorders in other breeds.
  • Diagnosis: breed, history, clinical signs, histopathology.
  • Treatment: chemotherapy and shampoo therapy.
  • Prognosis: guarded - lifelong condition.

Pathogenesis

Etiology



Primary form
  • Inherited.
Secondary form
  • Friction or intertrigo.
  • Endocrinopathy.
  • Hypersensitivity.

Pathophysiology

  • Genodermatosis in the Dachshund.
  • Cutaneous reaction to skin insult in secondary form.

Timecourse

  • Lifelong in Dachshund.
  • Depends upon initiating cause in secondary form.

Diagnosis

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Anderson R K (1979) Canine acanthosis nigricans. Comp Contin Educ Pract Vet 1, 466.


ADDED