ISSN 2398-2969      

Acanthosis nigricans

icanis
Contributor(s):

David Scarff


Introduction

  • Uncommon cutaneous reaction pattern.
  • Cause: inherited or due to hypersensitivity, trauma or endocrinopathy.
  • Signs: melanosis, acanthosis and lichenification in flexures, especially axilla Acanthosis nigricans.
  • Idiopathic in Dachshund.
  • Secondary feature with several skin disorders in other breeds.
  • Diagnosis: breed, history, clinical signs, histopathology.
  • Treatment: chemotherapy and shampoo therapy.
  • Prognosis: guarded - lifelong condition.

Pathogenesis

Etiology

Primary form

  • Inherited.

Secondary form

  • Friction or intertrigo.
  • Endocrinopathy.
  • Hypersensitivity.

Pathophysiology

  • Genodermatosis in the Dachshund.
  • Cutaneous reaction to skin insult in secondary form.

Timecourse

  • Lifelong in Dachshund.
  • Depends upon initiating cause in secondary form.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Anderson R K (1979) Canine acanthosis nigricans. Comp Contin Educ Pract Vet 1, 466.

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