Canis ISSN: 2398-2942

Cryptosporidium spp

Contributor(s): Vetstream Ltd

Introduction

Classification

Taxonomy

  • Phylum: Apicocomplexa.
  • Suborder: Eimeriina.
  • Family: Cryptosporidiidae.
  • Genus: Cryptosporidium.

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Clinical Effects

Epidemiology

Habitat

  • Oocysts are found in the feces of many animal species.
  • Other stages are obligate parasites in the intestinal tract.

Lifecycle

  • Similar to that of other intestinal coccidia:
    • Oocysts, each containing 4 sporozoites, liberated in feces.
    • Ingestion → sporozoites invade microvillous brush border of enterocytes.
    • Develop into trophozoites → differentiate → schizonts containing 4-8 merozoites.
    • Gametogeny follows 1-2 generations of schizogeny.
    • Oocysts produced in 72 hours.

Transmission

  • Oocysts by feco-oral route.

Pathological effects

  • Severity of disease depends on immunocompetence of host.
  • Blunting and fusion of intestinal villi → diarrhea.

Other Host Effects

  • Subclinical infection common.

Control

Control via chemotherapies

  • There is no known specific treatment.
  • Spiramycin may be of some value.

Control via environment

Potential for zoonotic infection

Diagnosis

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Dubey J P (1993) Intestinal protozoa infections. Vet Clin North Am Small Anim Pract 23 (1), 37-55 PubMed.
  • Moore J A, Blagburn B L, Lindsay D S (1988) Cryptosporidiosis in animals, including humans. Compendium on Continuing Education for the Practicing Veterinarian 10 (3), 275-287 VetMedResource.
  • Turnwald G H, Barta O, Taylor H W et al (1988) Cryptosporidiosis associated with immunosuppression attributable to distemper in a pup. J Am Vet Med Assoc​ 192 (1), 79-81 PubMed.
  • Moon H W, Woodmansee D B (1986) Cryptosporidiosis. J Am Vet Med Assoc​ 189 (6), 643-646 PubMed.

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