Bovis ISSN 2398-2993

Flunixin meglumine

Synonym(s): NSAID, non-steroidal anti-inflammatory drug

Contributor(s): Louise Cox-O’Shea, Vetstream Ltd , Andrea Tarr

Introduction

Name

  • Flunixin meglumine.
Note: In July 2018 the Veterinary Medicines Directorate suspended the supply of products, for food-producing animals, containing the excipient diethanolamine. This suspension affects many products containing flunixin. Full details may be found at: www.gov.uk/government/news/suspension-of-veterinary-medicines-containing-the-excipient-diethanolamine-dea.

Class of drug

  • Non-steroidal Anti-inflammatory

Description

Chemical name

  • 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid.

Molecular formula

  • C14H11F3N2O2.C7H17NO5.

Molecular weight

  •  491.5.

Physical properties

  • Flunixin meglumine is a white powder. It is available as a solution for injection and a pour-on solution.

Storage requirements

  • Between 2-25°C.

Uses

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Indications

  • Inflammation and pain.
  • Endotoxic Endotoxic shock.
  •  Respiratory disease in cattle (in conjunction with antibiotic therapy).
  •  Mastitis in cattle (in conjunction with antibiotic therapy).
  •  Anti-pyretic.

Administration

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Pharmocokinetics

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Precautions

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Interactions

With other drugs

  • Concurrent administration of glucocorticoids may increase the risk of gastro-intestinal ulceration.

Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Bishop Y (2005) Ed The Veterinary Formulary. 6th edn. Pharmaceutical Press. ISBN: 0-85369-579-2.
  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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