ISSN 2398-2993      

Anti-inflammatory drugs: overview

obovis

Synonym(s): Non-steroidal anti-Inflammatory drugs, NSAIDs, Corticosteroids, Topicals
 


Introduction

  • Anti-inflammatory drugs are used to reduce the signs of acute inflammation.
  • Usually they relieve pain and reduce swelling.
  • For the treatment of musculoskeletal disorders, anti-inflammatories act upon inflammatory mediators and modulators, eg:
    • Histamine.
    • Bradykinin.
    • Prostaglandins.
    • Leukotrienes.
    • Thromboxanes.
    • Platelet-activating factor.
    • Complement components.
    • Lysosomal and non-lysosomal enzymes.
    • Nitric oxide.
    • Oxygen derived free radicals.
  • Action may only suppress, not abolish, inflammatory effects of mediators.

Non steroidal Anti Inflammatory Drugs (NSAIDs)

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Corticosteroids

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Topical anti-inflammatory preparations

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