ISSN 2398-2993      

Bacillary hemoglobinuria

obovis
Contributor(s):

Mike Reynolds

John Tulloch

University of Liverpool logo

Synonym(s): clostridial diseases, clostridium hemolyticum, haemolyticum novyi type D


Introduction

  • Cause: Clostridia novyi type D.
  • Signs: acute death, rumen stasis, depression, reduced defecation, abdominal discomfort, passage of dark red urine, anemia, icterus.
  • Diagnosis: clinical and post mortem findings consistent with disease. Fluorescent antibody test on affected tissue.
  • Treatment: 25,000-40,000 IU procaine penicillin per kg body weight has been advocated. Non-steroidal anti-inflammatories and blood transfusions in some cases.
  • Prognosis: poor.

Pathogenesis

Etiology

  • Bacilliary hemoglobinuria is caused by Clostridia novyi type D Clostridium spp.

Predisposing factors

General

  • Cattle grazed on marsh or wet areas.
  • Spores may survive within hay and cause disease when fed to animals later in the season.

Specific

  • Migrating liver fluke (Fasciola hepatica) Fasciola hepatica, activating fungal spores.
    • Migrating liver fluke, activate quiescent spores within the liver parenchyma.
    • This leads to rapid spore multiplication and the mass release of toxin. This results in pronounced tissue damage and toxemia.

Timecourse

  • Hours.

Epidemiology

  • Occurs worldwide.
  • Mostly commonly occurs in grazed livestock of any age.
  • Normally sporadic in nature.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Prevention

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Mueller K (2015) Clostridial diseases in cattle and sheep. Cattle practice 23 (1), 127-131 VetMedResource.
  • Otter A & Davies I (2015) Disease features and diagnostic sampling of cattle and sheep post mortem examinations. In Pract 37, 293-305.
  • Harwood D G (2007) Clostridial disease in cattle: part 2. UK Vet 12 (2), 21-24.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code