Canis ISSN: 2398-2942

Blood biochemistry: total globulin

Synonym(s): TGG

Contributor(s): Kathleen P Freeman

Overview

Contains alpha-, beta- and gamma-globulin fractions.
Alpha- and beta- further subdivided into alpha-1 and -2 and beta-1 and -2.
Total gobulin is a calculated result ([total protein] Blood biochemistry: total protein minus [albumin] Blood biochemistry: albumin = total globulin).
Examination of individual fractions following electrophoretic separation more specific Serum protein electrophoresis.

Sampling

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Tests

Methodologies

Determined indirectly (calculated) by difference in total protein Blood biochemistry: total protein and albumin Blood biochemistry: albumin.
Electrophoretic separation Serum protein electrophoresis of proteins is necessary to determine individual fractions.

Availability

Readily available.
Contact individual commercial laboratories for availability of electrophoresis.

Technique (intrinsic) limitations

Must be interpreted in conjunction with other laboratory and clinical findings.

Technician (extrinsic) limitations

Electrophoresis is a specialized technique.

Result Data

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Further Reading

Publications

Refereed papers

Recent references from VetMed Resource and PubMed.
Day M J (1996) Serial monitoring of clinical, hematological and immunological parameters in canine autoimmune hemolytic anemia. JSAP 37(11), 523-534.

Other sources of information

Ettinger S J & Feldman E C (eds) (2000) Textbook of Veterinary Internal Medicine. 5th edn. Philadelphia: W B Saunders & Co.
Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.
Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa: Iowa University Press.

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