Canis ISSN: 2398-2942

Blood biochemistry: sodium

Synonym(s): Na

Contributor(s): Kathleen P Freeman

Overview

  • Present mainly in extracellular fluid but freely diffusible throughout ECF.
  • Usually excess in diet so dietary alterations unlikely to affect concentrations in body.
  • Controlled by kidneys and important in regulation of fluid balance.
  • As part of routine biochemical screening panel.
  • Sodium and chloride Blood biochemistry: chloride ions are the most osmotically active solute in plasma.
  • Measured in conjunction with other electrolytes, eg chloride Blood biochemistry: chloride and potassium Blood biochemistry: potassium , and bicarbonate (total CO2), where metabolic disturbances may be suspected, eg severe vomiting and diarrhea.
  • In combination with urine electrolyte concentrations for fractional electrolyte excretion Fractional electrolyte excretion in assessment of renal failure or other conditions.

Sampling

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Tests

Methodologies

  • Ion-specific electrode most commonly used.

Availability

  • Widely available at commercial laboratories.

Technique (intrinsic) limitations

  • Test results only significant in conjunction with other laboratory results and clinical findings.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Looney A L et al (1998) Use of hand-held device for analysis of blood electrolyte concentrations and blood gas partial pressures in dogs and horses. JAVMA 213(4), 526-530.

Other sources of information

  • Ettinger S J & Feldman E C (eds) (2000) Textbook of Veterinary Internal Medicine. 5th edn. Philadelphia: W B Saunders & Co.
  • Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.
  • Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa: Iowa University Press.


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