Canis ISSN: 2398-2942

Clindamycin

Contributor(s): Stephen Barr

Introduction

Name

  • Clindamycin.

Class of drug

  • Lincosamide antibiotic.

Description

Chemical name

  • (2S-trans)-methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-alpha-D-galacto-octopyranoside.

Molecular formula

  • C18H22ClN2O5S.

Physical properties

  • Multi-colored capsules.

Storage requirements

  • <25°C.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmocokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs



Cross-resistance
  • Complete cross-resistance between lincomycin Lincomycin and clindamycin.
  • Partial cross-resistance with erythromycin Erythromycin.
Non-depolarizing muscle relaxants, eg tubocurarine
  • May be increased by clindamycin.
Neostigmine and pyridostigmine Erythromycin
  • See also erythromycin Erythromycin.
  • Antagonize each other's effectsin vitro; clinical significance unknown.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

ADDED