Canis ISSN: 2398-2942

Skin: exfoliative cutaneous lupus erythematosus

Synonym(s): Hereditary lupoid dermatosis; ECLE

Contributor(s): David Scarff, Susan E Shaw, David Godfrey

Introduction

  • Cause: idiopathic.
  • Signs: scaling and crusting of the skin.
  • Familial in German short-haired pointer.
  • Diagnosis: breed, clinical signs, histopathology.
  • Treatment: anti-seborrheic baths, prednisolone.
  • Prognosis: incurable.

Pathogenesis

Pathophysiology

  • Idiopathic.
  • Unknown.

Timecourse

  • Persistent, may wax and wane.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Maudin E A, Morris D O, Bron D C et al (2010) Exfoliative cutaneous lupus erythematosus in German short-haired pointers: disease development, progression and evaluation of three immunomodulatory drugs (ciclosporin, hydroxychloroquine, and adalimumab) in a controlled environment. Vet Dermatol 21 (4), 373-382 PubMed.
  • Bryden S L, White S D, Dunston S M et al (2005) Clinical, histopathological and immunological characteristics of exfoliative cutaneous lupus erythematosus in 25 German short-haired pointers. Vet Dermatol 16 (4), 239-252 PubMed.
  • Vroom M W et al (1995) Lupoid dermatosis in five German Short-haired Pointers. Vet Dermatol (2),  93-8 VetMedResource.

Other sources of information

  • Scott D W, Miller W H & Griffin C E (1995)Small Animal Dermatology. 5th edn. Philadelphia: W B Saunders. ISBN 0 7216 4850 9.
  • Yager J A & Wilcock B P (1994)Color Atlas and Text of Surgical Pathology of the Dog and Cat. London: Wolfe Publishing, Mosby Year Book Europe. ISBN 0 7234 1827 6.
  • Gross T L, Irkhe P J & Walder E J (1992)Veterinary Dermatopathology. St Louis: Mosby Year Book. ISBN 0 8016 5809 8.


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