Canis ISSN: 2398-2942

Eye: chemical burns

Contributor(s): David L Williams

Introduction

  • Cause:
    • Alkalis'melt' the cornea and readily penetrate the eye Cornea ulcer 03.
    • Acidscoagulate proteins and penetration of the eye is limited Cornea ulcer 03.
    • Detergentsandalcohol, eg surgical spirit strip corneal epithelium so care must be taken when preparing the eye for surgery.
  • Treatment: flush with copious quantities of physiological saline.
  • Prognosis: alkali burns - poor; prolonged irrigation with saline and use of a collagenase inhibitor recommended. Reconstitute 2 ml EDTA blood collection tube with sterile water or serum and use for frequent irrigation. Hospitalization required.

Pathogenesis

Pathophysiology

  • Alkaline corneal injury causes profound collagenolysis without coagulation limiting the extent of chemical penetration.

Timecourse

  • Acute - collagenolysis.
  • Chronic - corneal scarring.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Dice P F & Cooley P L (1988) Use of contact lenses to treat corneal disease in small animals. Semin Vet Med Surg 3 (1), 46-51 PubMed.


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